A Waki Selected Research

Hypoxia (Hypoxemia)

12/2001	Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells.
1/2001	Greater resistance and lower contribution of free radicals to hypoxic neurotoxicity in immature rat brain compared to adult brain as revealed by dynamic changes in glucose metabolism.
8/2000	Posthypoxic reoxygenation-induced neurotoxicity prevented by free radical scavenger and NMDA/non-NMDA antagonist in tandem as revealed by dynamic changes in glucose metabolism with positron autoradiography.
5/2000	Neurotoxicity after hypoxia/during ischemia due to glutamate with/without free radicals as revealed by dynamic changes in glucose metabolism.
2/2000	Hypoxic but not ischemic neurotoxicity of free radicals revealed by dynamic changes in glucose metabolism of fresh rat brain slices on positron autoradiography.

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A Waki Research Topics

Disease

5	Neoplasms (Cancer) 12/2001 - 10/2000
5	Hypoxia (Hypoxemia) 12/2001 - 02/2000
2	Ischemia 05/2000 - 02/2000
1	Ehrlich Tumor Carcinoma 12/2001
1	Myocardial Ischemia (Ischemic Heart Diseases) 06/2001
1	Brain Neoplasms (Brain Tumor) 04/2001
1	Hypothermia 05/2000

Drug/Important Bio-Agent (IBA)

6	Glucose (Dextrose)FDA LinkGeneric 04/2001 - 02/2000
4	Free RadicalsIBA 01/2001 - 02/2000
4	N-Methylaspartate (NMDA)IBA 01/2001 - 02/2000
4	Free Radical ScavengersIBA 01/2001 - 02/2000
3	Neuroprotective AgentsIBA 01/2001 - 02/2000
2	Excitatory Amino AcidsIBA 08/2000 - 05/2000
2	Glutamic Acid (Glutamate)FDA Link 05/2000 - 02/2000
1	NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)IBA 12/2001
1	copper (II) diacetyl- di(N(4)- methylthiosemicarbazone)IBA 12/2001
1	Cytochrome-B(5) Reductase (Methemoglobin Reductase)IBA 12/2001
1	EnzymesIBA 12/2001
1	NAD (NADH)IBA 12/2001
1	Copper-62IBA 06/2001
1	Indicators and Reagents (Reagents)IBA 04/2001
1	UridineIBA 03/2001
1	HexokinaseIBA 03/2001
1	CarbonIBA 03/2001
1	Cysteine (L-Cysteine)FDA Link 03/2001
1	Methionine (L-Methionine)FDA Link 03/2001
1	LipidsIBA 02/2001
1	Phosphatidylcholines (Phosphatidylcholine)IBA 02/2001
1	Acetates (Acetic Acid Esters)FDA Link 02/2001
1	Dizocilpine Maleate (Dizocilpine)IBA 01/2001
1	Oxygen (Dioxygen)IBA 02/2000

Therapy/Procedure

1	Therapeutics 04/2001
1	Radiotherapy 10/2000